Synthesis and characterization of iodoazidobenzylpindolol.

Abstract

A high affinity beta-adrenergic ligand, iodoazidobenzylpindolol, was synthesized and characterized. The absorption spectrum of this compound changed markedly upon photolysis, consistent with decomposition of the azide group. This compound has a KD of 5--7 x 10(-10) M for the duck erythrocyte ghost beta-adrenergic receptor when measured in a competitive binding assay.

Cite this paper

@article{Rashidbaigi1982SynthesisAC, title={Synthesis and characterization of iodoazidobenzylpindolol.}, author={Abbas Rashidbaigi and Arnold E. Ruoho}, journal={Journal of pharmaceutical sciences}, year={1982}, volume={71 3}, pages={305-7} }