Synthesis and characterization of iodinated vasopressin antagonists which retain high affinity for the vasopressin receptor.

@article{Moore1984SynthesisAC,
  title={Synthesis and characterization of iodinated vasopressin antagonists which retain high affinity for the vasopressin receptor.},
  author={Marcie L. Moore and William F Huffman and Glenn D Roberts and S Rottschaefer and L Sulat and J S Stefankiewicz and F L Stassen},
  journal={Biochemical and biophysical research communications},
  year={1984},
  volume={121 3},
  pages={878-83}
}
The mono- and di-iodinated analogs of lysine and arginine vasopressin have been prepared previously but not well characterized chemically. Their biological activities are greatly reduced with respect to LVP or AVP. In this paper we report a convenient synthesis of iodinated AVP agonists and antagonists, their purification by high performance liquid… CONTINUE READING