Synthesis and characterization of chitosan derivatives with dual-antibacterial functional groups.

  title={Synthesis and characterization of chitosan derivatives with dual-antibacterial functional groups.},
  author={Zhihan Li and Fei Yang and Rendang Yang},
  journal={International journal of biological macromolecules},
With the aim to discover chitosan derivatives with enhanced antibacterial activity and good water solubility compared with natural chitosan, a novel O-quaternary ammonium N-acyl thiourea chitosan (OQCATUCS) bearing double antibacterial groups with different degrees of substitution has been synthesized. The derivative was characterized by FTIR, (13)C NMR, elemental analysis, XRD, TGA and zeta potential analysis. Water solubility was also investigated. The antimicrobial activities of chitosan and… CONTINUE READING
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