Synthesis and characterization of acetalated dextran polymer and microparticles with ethanol as a degradation product.

Abstract

In the field of drug delivery, pH-sensitive polymeric microparticles can be used to release therapeutic payloads slowly in extracellular conditions (pH 7.4) and faster in more acidic areas in vivo, such as sites of inflammation, tumors, or intracellular conditions. Our group currently uses and is further developing the pH-sensitive polymer acetalated… (More)
DOI: 10.1021/am3008888

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