Synthesis and characterization of a novel fluorescent and colorimetric probe for the detection of mercury (II) even in the presence of relevant biothiols

@inproceedings{GarcaBeltrn2015SynthesisAC,
  title={Synthesis and characterization of a novel fluorescent and colorimetric probe for the detection of mercury (II) even in the presence of relevant biothiols},
  author={Olimpo Garc{\'i}a-Beltr{\'a}n and Alejandra Rodr{\'i}guez and A. Trujillo and Alvaro F Ca{\~n}ete and Pabla Aguirre and Sebasti{\'a}n Gallego-Quintero and Marco T. Nu{\~n}ez and Margarita E. Aliaga},
  year={2015}
}
We present here a novel probe, coumarin 3-azomethine derivative (AGB), which can detect selectively mercuric ions (Hg) via a hydrolysis reaction promoted by these ions. Interestingly, the probe can be used to assess the response to Hg even in the presence of the most important biothiols-glutathione and cysteine—and could be used in the Hg—imaging in living cells. 2015 Elsevier Ltd. All rights reserved. Mercury is a heavy transition metal that generally possesses three distinct oxidation states… CONTINUE READING