Synthesis and characterisation of helical beta-peptide architectures that contain (S)-beta3-HDOPA(Crown Ether) derivatives.

@article{Dutot2008SynthesisAC,
  title={Synthesis and characterisation of helical beta-peptide architectures that contain (S)-beta3-HDOPA(Crown Ether) derivatives.},
  author={Laurence Dutot and Anne Gaucher and Khadidja Elkassimi and Jeremy Drapeau and Michel Wakselman and J. -P. Mazaleyrat and Cristina Peggion and Fernando Formaggio and C. Toniolo},
  journal={Chemistry},
  year={2008},
  volume={14 10},
  pages={3154-63}
}
A new set of beta-amino acids that carry various crown ether receptors on their side chains of the general formula (S)-beta(3)-HDOPA(crown ether) (HDOPA: homo-3,4-dihydroxyphenylalanine; (crown ether): [15]crown-5 ([15-C-5]), [18]crown-6 ([18-C-6]), [21]crown-7 ([21-C-7]), 1,2-Benzo-[24]crown-8 ([Benzo-24-C-8]) and (R)-Binol-[20]crown-6 ([(R)-Binol-20-C-6])) was prepared. Peptides that are based on these new crowned beta-amino acids combined with (1S,2S)-ACHC (2-aminocyclohexanecarboxylic acid… CONTINUE READING