Synthesis and characterisation of arsenic nanoparticles and its interaction with DNA and cytotoxic potential on breast cancer cells.

@article{Subastri2018SynthesisAC,
  title={Synthesis and characterisation of arsenic nanoparticles and its interaction with DNA and cytotoxic potential on breast cancer cells.},
  author={Ariraman Subastri and Viswanath Arun and Preeti Sharma and Ezhuthupurakkal Preedia Babu and Arumugam Suyavaran and Subramaniyam Nithyananthan and Ghedeir Muslem Alshammari and Balakrishnan Aristatile and Venkataraman Dharuman and Chinnasamy Thirunavukkarasu},
  journal={Chemico-biological interactions},
  year={2018},
  volume={295},
  pages={
          73-83
        }
}
Therapeutic applications of arsenic trioxide (ATO) are limited due to their severe adverse effects. However, nanoparticles of ATO might possess inimitable biologic effects based on their structure and size which differ from their parent molecules. Based on this conception, AsNPs were synthesized from ATO and comparatively analysed for their interaction mechanism with DNA using spectroscopic & electrochemical techniques. Finally, anti-proliferative activity was assessed against different breast… 
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