Synthesis and biological study of some new chalcone and pyrazole derivatives

S. Tala; P. B. Vekariya; R. M. Ghetiya; B. Dodiya; H. S. Joshi

Corpus ID: 96711667

Synthesis and biological study of some new chalcone and pyrazole derivatives

@inproceedings{Tala2013SynthesisAB,
  title={Synthesis and biological study of some new chalcone and pyrazole derivatives},
  author={S. Tala and P. B. Vekariya and R. M. Ghetiya and B. Dodiya and H. S. Joshi},
  year={2013}
}

S. Tala, P. B. Vekariya, +2 authors H. S. Joshi

Published 2013

Chemistry

Substituted chalcone and pyrazole derivatives have been synthesized by reacting 3-isopropyl-4-methoxybenzaldehyde with various aromatic ketones by using alkali as catalyst to afford (E)3-(3-Isopropyl-4-methoxyphenyl)-1-aryl-prop-2-en-1-ones 2a-j. Compounds 2a-j on reaction with hydrazine hydrate in the presence of glacial acetic acid give 1-acetyl-3-aryl-5-(3-isopropyl4-methoxyphenyl)pyrazoles 3a-j. The homogeneity of all the newly synthesized compounds has been checked by TLC. Their IR, H NMR… CONTINUE READING