Synthesis and biological properties of A-71497: a prodrug of tosufloxacin.

@article{Chu1990SynthesisAB,
  title={Synthesis and biological properties of A-71497: a prodrug of tosufloxacin.},
  author={Daniel T Chu and Isabella Lico and Robert N Swanson and Kennan C. Marsh and Jacob J. Plattner and Andre Pernet},
  journal={Drugs under experimental and clinical research},
  year={1990},
  volume={16 9},
  pages={435-43}
}
Tosufloxacin (5, A-61827 tosylate or T-3262) is currently under product development by both Abbott Laboratories and Toyama Chemical Co. Its registration as antibacterial agent has been approved in Japan. It has been found to be extremely effective in treating several bacterial infections. However, due to its inherent low water solubility, the development of… CONTINUE READING