Synthesis and biological evaluation of novel exo-methylene cyclopentanone tetracyclic diterpenoids as antitumor agents.

@article{Li2011SynthesisAB,
  title={Synthesis and biological evaluation of novel exo-methylene cyclopentanone tetracyclic diterpenoids as antitumor agents.},
  author={Jing Li and Dayong Zhang and Xiaoming Wu},
  journal={Bioorganic & medicinal chemistry letters},
  year={2011},
  volume={21 1},
  pages={130-2}
}
The structure of exo-methylene cyclopentanone, which exists in nature tetracyclic diterpenoids products, has been proved to be an innate group for the treatment of cancer and inflammation. In this letter, four different scaffolds of tetracyclic diterpenoids including the structure exo-methylene cyclopentanone were synthesized from steviol and isosteviol and… CONTINUE READING