Synthesis and biological evaluation of new bischromone derivatives with antiproliferative activity.


The synthesis of new bischromone derivatives (4a-c and 5a-c) as potential anticancer drugs is described. The difference in the reactivity between 4-oxo-4H-chromene-3-carboxylic acid 2 (or its methyl ester 3) and 4-oxo-4H-chromene-3-carbonyl chloride 1 with three different polyamines: 3,3'-diamino-N-methyldipropylamine (a), 1,4-bis(3-aminopropyl)piperazine… (More)
DOI: 10.1002/ardp.201200220


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Citations per Year

Citation Velocity: 11

Averaging 11 citations per year over the last 2 years.

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