Synthesis and biological evaluation of new 2,3-dihydrothiazole derivatives for antimicrobial, antihypertensive, and anticonvulsant activities.

@article{Omar1984SynthesisAB,
  title={Synthesis and biological evaluation of new 2,3-dihydrothiazole derivatives for antimicrobial, antihypertensive, and anticonvulsant activities.},
  author={Abdelsattar M. Omar and N. H. Eshba},
  journal={Journal of pharmaceutical sciences},
  year={1984},
  volume={73 8},
  pages={
          1166-8
        }
}
A novel series of 2-arylimino-2,3-dihydrothiazole derivatives, substituted in the 3-position with a beta-phenethyl moiety and the 4-position with substituted aryl functions, was synthesized as potential antimicrobial, antihypertensive and anticonvulsive agents. While no antimicrobial or significant antihypertensive activity was observed for the products, XII, XIII, and XXI displayed potent anticonvulsant activity. 
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30 Citations

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