Synthesis and biological evaluation of diamine-based histamine H3 antagonists with serotonin reuptake inhibitor activity.

Abstract

The synthesis and structure-activity relationships of a series of novel phenoxyphenyl diamine derivatives with affinity for both the histamine H(3) receptor and the serotonin transporter is described.

Cite this paper

@article{Stocking2007SynthesisAB, title={Synthesis and biological evaluation of diamine-based histamine H3 antagonists with serotonin reuptake inhibitor activity.}, author={Emily M Stocking and Jennifer M Litt Miller and Ann J. Barbier and Sandy Wilson and Jamin D. Boggs and Heather M Mcallister and Jiejun Wu and Timothy W. Lovenberg and Nicholas I. Carruthers and Ronald L Wolin}, journal={Bioorganic & medicinal chemistry letters}, year={2007}, volume={17 11}, pages={3130-5} }