Synthesis and biological evaluation of coumarin derivatives containing imidazole skeleton as potential antibacterial agents.

Abstract

Emergence of multidrug-resistant bacteria causes an urgent need for new generation of antibiotics, which may have a different mechanism of inhibition or killing action from the existing. Here, we report on the design, synthesis, and biological evaluation of thirty-nine coumarin derivatives in order to solve the antibacterial resistance by targeting at the… (More)
DOI: 10.1016/j.ejmech.2017.11.100

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