Synthesis and biological activity of phosphoglycolipids from Thermus thermophilus.

Abstract

An extreme thermophile, Thermus thermophilus, has very unique glycolipids on the cell surface. The acidic immunostimulatory phosphoglycolipid of T. thermophilus was synthesized for the first time, with newly developed glycosylation methods using 3-nitropyridyl (3NPy) and 4,6-dimethoxy-1,3,5-triazin-2-yl (DMT) glycosides as glycosyl donors. The analogues of… (More)
DOI: 10.1039/c3ob40899j

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@article{Fujimoto2013SynthesisAB, title={Synthesis and biological activity of phosphoglycolipids from Thermus thermophilus.}, author={Yukari Fujimoto and Kunihiro Mitsunobe and Satoko Fujiwara and Motoko Mori and Masahiro Hashimoto and Yasuo Suda and Shoichi Kusumoto and Koichi Fukase}, journal={Organic & biomolecular chemistry}, year={2013}, volume={11 30}, pages={5034-41} }