Synthesis and biological activity of benzoylmethylthio derivatives of pyridine, quinoline, and acridine

Abstract

It was determined that compounds Vl, VII, X-XII, and XVI-XVIII, XlX inhibit the reproduction of the HSV in the CEF cell culture. Compounds VI and XI at 10 ~g/ml reduce the infection titer of the virus by 1.5 log TCDs0 relative to a control culture: the remaining compounds reduce the infection titer by 1.0-1.25 log TCDs0 at concentrations from 5 to i0 ~g/ml… (More)
DOI: 10.1007/BF00772103

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