Synthesis and biological activity of 26-norbrassinolide, 26-norcastasterone and 26-nor-6-deoxocastasterone.

@article{Watanabe2001SynthesisAB,
  title={Synthesis and biological activity of 26-norbrassinolide, 26-norcastasterone and 26-nor-6-deoxocastasterone.},
  author={Tomoyuki Watanabe and Testsuro Noguchi and Takao Yokota and Kyomi Shibata and Hiroyuki Koshino and Hideharu Seto and Seong-Ki Kim and Suguru Takatsuto},
  journal={Phytochemistry},
  year={2001},
  volume={58 2},
  pages={
          343-9
        }
}
26-Norbrassinolide, identified as a metabolite of brassinolide in cultured cells of the liverwort, Marchantia polymorpha, as well as 26-norcastasterone and 26-nor-6-deoxocastasterone were synthesized. Synthesis of these new brassinosteroids was conducted by employing the orthoester Claisen rearrangement and asymmetric dihydroxylation as key reactions. The modified rice lamina inclination test indicated that these three 26-norbrassinosteroids were less active than their corresponding C28… CONTINUE READING