Synthesis and antiviral activity of some new bis-1,3-thiazole derivatives.

@article{Dawood2015SynthesisAA,
  title={Synthesis and antiviral activity of some new bis-1,3-thiazole derivatives.},
  author={Kamal Mohamed Dawood and Taha M. A. Eldebss and Heba S A El-Zahabi and Mahmoud H Yousef},
  journal={European journal of medicinal chemistry},
  year={2015},
  volume={102},
  pages={266-76}
}
Treatment of 3-phenyl-1,3-thiazolidin-4-one derivative 1 with phenylisothiocyanate in DMF, in the presence of potassium hydroxide, at room temperature gave the non-isolable potassium salt 2. The in-situ reaction of 2 with differently substituted N-aryl hydrazonoyl chlorides 3, 7a-d and 14a-d afforded the corresponding 2-(pyrazolyl)thiazolylimino-5… CONTINUE READING