Synthesis and antiviral activity evaluation of some new 6-substituted 3-(1-adamantyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles.

@article{Kritsanida2002SynthesisAA,
  title={Synthesis and antiviral activity evaluation of some new 6-substituted 3-(1-adamantyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles.},
  author={Marina Kritsanida and Anastasia Mouroutsou and Panagiotis Marakos and Nicole Pouli and Spyroula Papakonstantinou-Garoufalias and C Pannecouque and Myriam Witvrouw and Erik de Clercq},
  journal={Farmaco},
  year={2002},
  volume={57 3},
  pages={
          253-7
        }
}
A number of novel 3,6-disubstituted 1,2,4-triazolo[3,4-b][1,3,4]thiadiazole derivatives, containing the adamantyl moiety, were synthesized and examined in various viral test systems. No antiviral effects were noted with any of the compounds at subtoxic concentrations in cell culture. 
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