Synthesis and antitumor activity of ammine/amine platinum(II) and (IV) complexes.

@article{Khokhar1993SynthesisAA,
  title={Synthesis and antitumor activity of ammine/amine platinum(II) and (IV) complexes.},
  author={Abdul R. Khokhar and Yonghong Deng and Salaam Al-Baker and Motofumi Yoshida and Zahid H. Siddik},
  journal={Journal of inorganic biochemistry},
  year={1993},
  volume={51 3},
  pages={677-87}
}
Dimeric platinum complexes, [Pt(RNH2)I2]2 (where R = H, methyl, ethyl, isopropyl, cyclopropyl, cyclobutyl, cyclopentyl, and cyclohexyl), have been synthesized by reactions of diiodoplatinum compounds with perchloric acid in water/ethanol solutions. The dimerization varies from several hours to a few days depending upon the length of the carbon chain in the… CONTINUE READING