Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II.

  title={Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II.},
  author={Dorina Mantu and Mihaela Catalina Luca and Costel Moldoveanu and Gheorghita N. Zbancioc and Ionel Mangalagiu},
  journal={European journal of medicinal chemistry},
  volume={45 11},
A series of eighteen novel compounds with pyridazine moiety were synthesized and their in vitro antituberculosis activities have been evaluated. A fast, general, and facile method for preparation of pyridazine derivatives in moderate to excellent yields is presented. Three compounds were found to be moderate active against Mycobacterium tuberculosis. Correlation of structure-biological activity has been done. 
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