Synthesis and antioxidant activity of 1,3,4-oxadiazole tagged thieno[2,3-d]pyrimidine derivatives.

@article{Kotaiah2012SynthesisAA,
  title={Synthesis and antioxidant activity of 1,3,4-oxadiazole tagged thieno[2,3-d]pyrimidine derivatives.},
  author={Y Kotaiah and N. Harikrishna and Kerru Nagaraju and Chunduri Venkata Rao},
  journal={European journal of medicinal chemistry},
  year={2012},
  volume={58},
  pages={340-5}
}
This study represents the synthesis of a new series of N-substituted phenyl-5-methyl-6-(5-(4-substituted phenyl)-1,3,4-oxadiazol-2-yl)thieno[2,3-d]pyrimidin-4-amine derivatives (4a-l) and substituted phenylamino-5-methylthieno[2,3-d]pyrimidine-6-carboxylic acid derivatives (3a-d). The newly synthesized compounds were characterized by (1)H NMR, (13)C NMR, LC-MS and IR analyses. All these novel compounds were screened for their in vitro antioxidant activity by employing DPPH, hydrogen peroxide… CONTINUE READING

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