Synthesis and antimycobacterial activity of carbamate derivatives of 1,2-oxazine

Abstract

Aseries of carbamate derivatives of 1,2-oxazine was obtained by means of [2 + 4]-cycloaddition of 1,3-dienes to C-nitroso-alkyl-N-arylcarbamates. The antimycobacterial activity of the synthesized compounds with respect to Mycobacterium tuberculosis and Mycobacterium lufu species was studied in vitro in comparison to isoniazid and dapsone. The activity of… (More)
DOI: 10.1007/s11094-006-0132-5

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