Synthesis and antimicrobial screening of novel series of imidazo-[1,2-a]pyridine derivatives

@article{Desai2012SynthesisAA,
  title={Synthesis and antimicrobial screening of novel series of imidazo-[1,2-a]pyridine derivatives},
  author={Nisheeth C. Desai and M. R. Pandya and Kiran M Rajpara and Vivek V Joshi and Hasit V Vaghani and Hitesh M Satodiya},
  journal={Medicinal Chemistry Research},
  year={2012},
  volume={21},
  pages={4437-4446}
}
In an attempt to find new bio-active molecules, a series of mannich bases N,N-dimethyl-1-(7-methyl-2-(aryl)imidazo[1,2-a]pyridin-3-yl)methanamines 4a–l were synthesized by mannich reaction of 7-methyl-2-(aryl)imidazo-[1,2-a]pyridines 3a–l with paraformaldehyde and N,N-dimethyl amine. Compounds 3a–l were prepared from reaction between different substituted 2… CONTINUE READING