Synthesis and antimicrobial evaluation of novel substituted pyrimidine scaffold

@article{Ghodasara2013SynthesisAA,
  title={Synthesis and antimicrobial evaluation of novel substituted pyrimidine scaffold},
  author={Hardik B. Ghodasara and Amit R. Trivedi and Vipul B. Kataria and Bharat Gordhanbhai Patel and Viresh H. Shah},
  journal={Medicinal Chemistry Research},
  year={2013},
  volume={22},
  pages={6121-6128}
}
Synthesis and biological evaluation of substituted pyrimidine derivatives containing 4-amino and 5-cyano substituted derivatives are described. Biginelli typed three component reactions between an aldehyde, malononitrile, and a urea constituent give a rapid facile pyrimidine ring. The constitution of the products has been delineated by elemental analysis… CONTINUE READING