Synthesis and antimicrobial action of some bis-thiazolidines.

Abstract

alpha, delta-Bis(thiazolidinidione-2,4-hydrazone-4-yl-3)butane (1) was reacted with heterocyclic and aromatic aldehydes in boiling glacial acetic acid, where the corresponding analogs of alpha, delta-bis (thiazolidindione-2,4-N-arylidenehydrazone-4-yl-3)butane (2) were separated. While with some other heterocyclic and aromatic aldehydes, and under the same conditions, the corresponding analogs of alpha, delta-bis(thiazolidinidione-2,4-N-arylidenehydrazone-4-arylidene-5-yl-3) butane (3) were obtained. The synthesized compounds exhibit antimicrobial activity.

Cite this paper

@article{Salama1979SynthesisAA, title={Synthesis and antimicrobial action of some bis-thiazolidines.}, author={Hediat M.H. Salama and H V Vladzimirska and N. M. Turkevich and P N Stebljuk}, journal={Die Pharmazie}, year={1979}, volume={34 11}, pages={720-1} }