Synthesis and antiinflammatory activity of 2-Methyl-5-[ω-phenylacyl]coumarans

Abstract

Ketones II-IV were synthesized by the Friedel-Crafts reaction by acylation of 2-methylcoumaran (compound I) with the chloranhydrides of to-phenylalkane acids in the presence of anhydrous aluminum chloride. The structures of the newly synthesized compounds II-IV were confirmed by UV, IR, and PMR spectral data; the starting compound, I, has been described… (More)
DOI: 10.1007/BF02219796

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