Synthesis and antifungal evaluation of some 3-phenyl-2,5-disubstituted indoles derived from new ethyl-2-benzyl-2-[N-(aryl)hydrazono] ethanoates.

@article{Ergenc1990SynthesisAA,
  title={Synthesis and antifungal evaluation of some 3-phenyl-2,5-disubstituted indoles derived from new ethyl-2-benzyl-2-[N-(aryl)hydrazono] ethanoates.},
  author={Nilay Ozeyranli Ergenc and Ahmed E. Salman and Aysel G{\"u}rsoy and G Bankaoğlu},
  journal={Die Pharmazie},
  year={1990},
  volume={45 5},
  pages={346-7}
}
In connection with previous related works [1-6] we have now studied the reaction of ethyl alpha-benzyl-alpha-acetylethanoate (EBAE), as an aliphatic active C-H compound, with the diazonium salts of p-aminobenzoic acid (PABA), sulfanilamide (SA) and N,N-dimethylsulfanilamide (DSA), respectively. Ethyl 2-benzyl-2-[N-(aryl)hydrazono] ethanoates were the resulting substances (1-3). The synthesis of 4-6, namely 3-phenyl-2,5-disubstituted indoles, was carried out employing acidic indole ring closure… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…