Synthesis and antidiabetic properties of chitosan-stabilized selenium nanoparticles.

@article{Zeng2018SynthesisAA,
  title={Synthesis and antidiabetic properties of chitosan-stabilized selenium nanoparticles.},
  author={Siqi Zeng and Yu Ke and Yixi Liu and Yingbin Shen and Lan Zhang and Cheng Li and Aiping Liu and Li-tao Shen and Xinjie Hu and Hejun Wu and Wenjuan Wu and Yuntao Liu},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2018},
  volume={170},
  pages={
          115-121
        }
}
  • Siqi Zeng, Yu Ke, +9 authors Yuntao Liu
  • Published 1 October 2018
  • Medicine, Chemistry
  • Colloids and surfaces. B, Biointerfaces
Chitosan-stabilized selenium nanoparticles (CTS-SeNPs) were prepared through the reduction of selenite acid with ascorbic acid. The optimal synthesis conditions of CTS-SeNPs were obtained by orthogonal experiments. Besides, the size, morphology and stability of CTS-SeNPs were characterized by transmission electron microscopy (TEM), scanning electron microscope (SEM) and dynamic light scattering (DLS). The results showed that, the CTS-SeNPs with diameter of about 54 nm could be obtained under… Expand
Synthesis, characterization, in vitro antioxidant and hypoglycemic activities of selenium nanoparticles decorated with polysaccharides of Gracilaria lemaneiformis.
  • Li Tang, Xiaomin Luo, +4 authors Yongguang Bi
  • Medicine
  • International journal of biological macromolecules
  • 2021
TLDR
In vitro cytotoxicity assay and hemolysis activity examinations indicated that GLPs-SeNPs have excellent biocompatibility and might be used as a potential antioxidant agent and antidiabetic agent for food and medical applications. Expand
Characterization of selenium oxide nanofiller effect on the spectroscopic and thermal properties of Cs/PAM nanocomposites
Abstract Nanocomposite samples of chitosan (Cs)/polyacrylamide (PAM) blend incorporated with different concentrations of selenium oxide (SeO2) nanoparticles were fabricated and investigated. TheExpand
Digestion and absorption properties of Lycium barbarum polysaccharides stabilized selenium nanoparticles.
  • Jixian Zhang, Xue Yang, +6 authors Xin Xu
  • Medicine
  • Food chemistry
  • 2021
TLDR
The experiments of the intestinal sac model showed that LBP-SeNPs can better promote the absorption of selenium in various parts (duodenum, jejunum and ileum) of the intestine and the LBP can help to improve the structural stability of SeNPs in the digestion process and improve the bioavailability ofSelenium. Expand
Selenium nanostructure: Progress towards green synthesis and functionalization for biomedicine
Selenium is a pivotal micronutrient required for the proper functioning of the body. Deficiency of Se leads to various diseases whereas a high dosage of Se possesses toxicity. To reduce the toxicExpand
Catalytical degradation of industrial dyes using biosynthesized selenium nanoparticles and evaluating its antimicrobial activities
The release of textile dyes from the industries to the environment has become a significant health issue to humans and their surroundings, where a large number of dyes are wasted to the nearby waterExpand
Evaluation of antidiabetic effect of nanoselenium in STZ induced diabetes in rats
TLDR
Investigation of the anti-diabetic effects of selenium nanoparticles at dose 2 mg/kg body weight in streptozotocin induced diabetes in rats found they were able to prevent pancreatic tissue atrophy in island of Langerhans cells compared to uncontrolled group. Expand
Role of Nano-Selenium in Health and Environment.
TLDR
The procedure of selenium nanoparticle synthesis, characterization, and characterization is reviewed, with the emphasis on its role and application in health and environment. Expand
Chitosan oligosaccharide-g-linalool polymer as inhibitor of hyaluronidase and collagenase activity.
TLDR
The results revealed that the derivatives of chitosan oligosaccharide modified by grafting Linalool on its backbone exhibited higher thermal stability and more remarkable anti-inflammatory property against hyaluronidase and collagenase than that of COS. Expand
Potentialities of selenium nanoparticles in biomedical science
Nanotechnology is defined as the branch of science dealing with extremely small-sized particles with a size in the range of 1–100 nm, which are termed nanoparticles. Due to the extremely small sizeExpand
Chitosan-stabilized selenium nanoparticles alleviate cardio-hepatic damage in type 2 diabetes mellitus model via regulation of caspase, Bax/Bcl-2, and Fas/FasL- pathway.
TLDR
It is concluded that the combined strategy applied in the current study have a potential role to limit the diabetic complications and restore insulin resistance to a higher extent than monotherapeutic strategy and could be considered a promising therapeutic alternative in T2DM rat model. Expand
...
1
2
3
...

References

SHOWING 1-10 OF 39 REFERENCES
Synthesis and antioxidant properties of chitosan and carboxymethyl chitosan-stabilized selenium nanoparticles.
TLDR
The results revealed that the monodispersible SeNPs were ligated with CS and CCS to form nanocomposites in aqueous solution for at least 30 days, and for 120 days the nanoparticles increased to 180 nm or so in size. Expand
Synthesis, characterization, and controlled release of selenium nanoparticles stabilized by chitosan of different molecular weights.
TLDR
It is found that both low and high molecular weight chitosan-stabilized selenium nanoparticles exhibited core-shell microstructures with a size of about 103 nm after 30 days growing through the "bottom-up approach" and "top-down approach," respectively. Expand
Synthesis and antioxidant properties of gum arabic-stabilized selenium nanoparticles.
TLDR
It was concluded that the branched structure of GA was a significant factor for the functionality of GA-SeNPs and its efficiency in stabilizing SeNPs was compared with GA. Expand
Construction of selenium nanoparticles/β-glucan composites for enhancement of the antitumor activity.
TLDR
The size effect of SeNPs on anti-tumor activity was revealed that the SeNBP with more evenly particle size distribution show the higher anticancer activity. Expand
Creation of highly stable selenium nanoparticles capped with hyperbranched polysaccharide in water.
TLDR
This work provided reaction sites for the complexation between HBP and Se to fabricate well-dispersed Se nanoparticles in aqueous system with potential bioapplications and supported by the results of FTIR, TEM, AFM, and DLS. Expand
Immunomodulatory of selenium nano-particles decorated by sulfated Ganoderma lucidum polysaccharides.
TLDR
Results suggest that SeNPs-SPS complexes have anti-inflammatory potential modulating pro-/anti-inflammation cytokine secretion profiles, and that the mechanism is partially due to inhibition of activations of NF-κB, JNK1/2 and p38 MAPKs. Expand
Preparation, characterization and evaluation of selenite-loaded chitosan/TPP nanoparticles with or without zein coating
The selenite-loaded chitosan (CS) nanoparticles using tripolyphosphate (TPP) as a cross-linking agent with or without zein (a water insoluble corn protein) coating were prepared to obtain seleniteExpand
Antioxidant and cytotoxic effect of biologically synthesized selenium nanoparticles in comparison to selenium dioxide.
TLDR
Lower cytotoxicity of the biogenic Se NPs on MCF-7 cell line was confirmed and data obtained from reducing power assay revealed higher electron-donating activity of SeO2 compared to SeNPs, while the obtained results showed that, at the same concentration of 200μg/mL, Se Nps and SeO 2 represented scavenging activity. Expand
Selenium nanoparticles fabricated in Undaria pinnatifida polysaccharide solutions induce mitochondria-mediated apoptosis in A375 human melanoma cells.
TLDR
Treatment of A375 human melanoma cells with the Nano-Se resulted in dose-dependent cell apoptosis as indicated by DNA fragmentation and phosphatidylserine translocation, and further investigation on intracellular mechanisms found that Nano- Se treatment triggered apoptotic cell death in A375 cells withThe involvement of oxidative stress and mitochondrial dysfunction. Expand
Modification and modulation of saccharides on elemental selenium nanoparticles in liquid phase
Abstract The modification and modulation of saccharides on elemental selenium (Se 0 ) nanoparticles in liquid phase were studied. The saccharides, such as monosaccharide (glucose), oligosaccharideExpand
...
1
2
3
4
...