Synthesis and anticonvulsant activity of some novel fused heterocyclic 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives.

@article{Husain2009SynthesisAA,
  title={Synthesis and anticonvulsant activity of some novel fused heterocyclic 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives.},
  author={A. Jahir Husain and Mohammad A Naseer and Mohammad Sarafroz},
  journal={Acta poloniae pharmaceutica},
  year={2009},
  volume={66 2},
  pages={135-40}
}
In the present investigation, a series of 3,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivatives (6a-t) were synthesized and evaluated for their anticonvulsant activity and neurotoxicity. The structures of synthesized compounds were confirmed on the basis of their elemental analysis and spectral data results. In anti-MES activity compounds 6b, 6c… CONTINUE READING