Synthesis and anticancer activity of (E)-2-benzothiazole hydrazones.

Abstract

Benzothiazole hydrazones have been synthesized and evaluated for their in vitro antiproliferative activity against three human cancer cell lines: HL-60 (leukemia), MDAMB-435 (breast) and HCT-8 (colon). The good cytotoxicity for the three cancer cell lines and theoretical profile of compounds 3o and 3p pointed them as promising lead molecules for anticancer… (More)
DOI: 10.1016/j.ejmech.2014.08.039

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