• Corpus ID: 99122443

Synthesis and anticancer activity of 2, 4-disubstituted furo[3,2-b]indole derivatives

@inproceedings{2013SynthesisAA,
  title={Synthesis and anticancer activity of 2, 4-disubstituted furo[3,2-b]indole derivatives},
  author={莊仕弘 and 連金城 and 郭盛助 and 黃麗嬌},
  year={2013}
}

Design of New 2,4-Substituted Furo [3,2-B] Indole Derivatives as Anticancer Compounds Using Quantitative Structure-Activity Relationship (QSAR) and Molecular Docking

TLDR
The QSAR analysis showed that compound 15 has the best predicted anticancer activity, supported by molecular docking results that showed hydrogen bond interaction with essential amino acids to build anticancers activity such as MET769, THR830, and THR766 residues.

TFA-catalyzed Q-Tube Reactor-Assisted Strategy for the Synthesis of Pyrido[1,2-b][1,2,4]triazine and Pyrido[1′,2′:2,3][1,2,4]triazino[5,6-b]indole Derivatives

TLDR
X-ray single-crystal analysis was utilized in this study to authenticate the structure of the synthesized products and was found to be superb in comparison to that under the traditional refluxing conditions.

Fe3O4 magnetic nanoparticles (MNPs) as an effective catalyst for synthesis of indole derivatives

The principal aim of this research is the application of Fe3O4 (MNPs) in the synthesis of some indole derivatives. Fe3O4 MNPs were prepared by Co-Precipitation method from the reaction of FeCl2.4H2O

Synthesis and SAR studies of novel 6,7,8‐substituted 4‐substituted benzyloxyquinolin‐2(1H)‐one derivatives for anticancer activity

TLDR
Four new 4‐Phenylquinolin‐2(1H)‐one derivatives can induce cancer cell apoptosis and were investigated as more effective, less toxic antitumour agents.

SYNTHESIS AND CYTOTOXIC STUDIES OF 2, 3-DIMETHYLINDOLES AND TETRAHYDROCARBAZOLES

Objective: The objective of this study was to report the synthesis of 2,3-dimethylindoles and tetrahydrocarbazoles via Fisher indole synthesis and evaluation of their the anticancer properties.