Synthesis and Stereochemical Assignment of (+)-Chamuvarinin

@inproceedings{Florence2011SynthesisAS,
  title={Synthesis and Stereochemical Assignment of (+)-Chamuvarinin},
  author={Gordon J Florence and Joanne Morris and Ross G. Murray and Jonathan D. Osler and V. Raghunatha Reddy and Terry K. Smith},
  booktitle={Organic letters},
  year={2011}
}
A stereocontrolled total synthesis of (+)-chamuvarinin, isolated from the root extract of Uvaria Chamae, utilizes a convergent modular strategy to construct the adjacently linked C15-C28 ether array, followed by a late-stage Julia-Kocienski olefination to append the butenolide motif. This constitutes the first total synthesis of (+)-chamuvarinin, defining… CONTINUE READING