Synthesis and Photophysical and Photocatalytic Properties of a Highly Fluorinated and Durable Phthalocyanine-Peptide Bioconjugate for Potential Theranostic Applications.

Abstract

The functionalized, asymmetric fluoro-fluoroalkyl scaffold F48H7COOHPcZn (3) was used to prepare F48H7COOPcZn-6-amino-hexanoate-CTVALPGGYVRVC (5), a Pep42 peptide bioconjugate envisioned for photodynamic therapy, which can specifically target the GRP78 chaperone protein overexpressed and exclusively localized on some cancer cell surfaces. The analogous… (More)
DOI: 10.1021/acs.inorgchem.7b00847

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Cite this paper

@article{Carrin2017SynthesisAP, title={Synthesis and Photophysical and Photocatalytic Properties of a Highly Fluorinated and Durable Phthalocyanine-Peptide Bioconjugate for Potential Theranostic Applications.}, author={Erik N Carri{\'o}n and Jenyffer Santiago and David Sabatino and Sergiu M Gorun}, journal={Inorganic chemistry}, year={2017}, volume={56 12}, pages={7210-7216} }