Synthesis and Pharmacological Activity of N-[β-(para-substituted benzoyl)ethyl]isoleucine and -Methionine

Abstract

A series of N-[β-(p-substituted benzoyl)ethyl]-isoleucine and -methionine derivatives have been synthesized via the alkylation of amino acids with p-substituted β-diethylaminopropiophenone hydrochlorides. Some of the synthesized compounds possess significant antiinflammatory activity.

DOI: 10.1007/s11094-005-0156-2

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Cite this paper

@article{Agababyan2005SynthesisAP, title={Synthesis and Pharmacological Activity of N-[β-(para-substituted benzoyl)ethyl]isoleucine and -Methionine}, author={A. G. Agababyan and A. Y. Isakhanyan and O. A. Papoyan and A. E. Tumadzhyan and A. S. Balasanyan and G . A . Gevorgyan}, journal={Pharmaceutical Chemistry Journal}, year={2005}, volume={39}, pages={364-366} }