Synthesis and Hypoglycemic Activity of some Phthalimide Derivatives

@inproceedings{Mahapatra2010SynthesisAH,
  title={Synthesis and Hypoglycemic Activity of some Phthalimide Derivatives},
  author={S. P. Mahapatra and P. Ghode and Dinesh Kumar Jain and Subhash Chandra Chaturvedi and Bhim Chandra Maiti and Tapan Kumar Maity},
  year={2010}
}
N-hydroxyethyl phthalimide (PE-I) was prepared by refluxing phthalic anhydride with ethanolamine. 3phthalimidoethyl substituted benzoic acids (PE-II) were prepared by refluxing N-hydroxyethyl phthalimide with substituted benzoic acids. The corresponding acid chlorides (PE-III) were condensed with benzilidine-4acetophenone derivatives to afford the 3-(phthalimidoethyl)-4-substituted cinnamoyl substituted benzanilides (PEIV-1, 2, 4, 6, 9, PE-V-2, 4, 9). The compounds were screened for the in… CONTINUE READING

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