Synthesis and Anti-cancer Activity of Novel Thiazolidinone Analogs of 6-Aminoflavone.


Novel heterocyclic analogs were synthesized by combining a flavone nucleus and thiazolidinone ring in an effort to potentiate the existing anti-cancer activity of flavone. The syntheses of 6-aminoflavone, 6-amino-3-methoxyflavone, 6-amino-3-methoxy-3',4'-dimethxyflavone and their corresponding thiazolidinone analogs were performed. Fifteen novel analogs… (More)
DOI: 10.1248/cpb.c15-00454