Synthesis and Anthelmintic and Insecticidal Activities of 1-R-3-Methyl-6-Methoxy-7-( P-Propoxy)-3,4-Dihydroisoquinoline Hydrochlorides

1-R-3-Methyl-6-methoxy-7-(n-propoxy)-3,4-dihydroisoquinolines were synthesized via cyclocondensation of O-n-propyleugenol with various nitriles. It was shown that the hydrochlorides of the synthesized compounds exhibited anthelmintic and weak insecticidal activity. The isoquinoline containing a 1-benzyl radical had the greatest anthelmintic activity and was… CONTINUE READING