Synthesis , Inhibition of Mycobacterium tuberculosis Enoyl-acyl Carrier Protein Reductase and Antimycobacterial Activity of Novel Pentacyanoferrate ( II )-isonicotinoylhydrazones

@inproceedings{Gazzi2017SynthesisI,
  title={Synthesis , Inhibition of Mycobacterium tuberculosis Enoyl-acyl Carrier Protein Reductase and Antimycobacterial Activity of Novel Pentacyanoferrate ( II )-isonicotinoylhydrazones},
  author={Thais P. Gazzi and Mariane Rotta and Anne Drumond Villela and Valn{\^e}s S Rodrigues-Junior and Leonardo Kr{\'a}s Borges Martinelli and Francisco Adilson Matos Sales and Eduardo Henrique Silva Sousa and Maria Martha Campos and Luiz Augusto Basso and Di{\'o}genes Santiago Santos and Pablo Machado},
  year={2017}
}
Tuberculosis remains among the top causes of death triggered by a single pathogen. Herein, a greener synthetic approach for isonicotinoylhydrazones is described using ultrasound energy. These compounds were used as starting materials for synthesizing pentacyanoferrate(II)isonicotinoylhydrazones, which inhibited the reaction catalyzed by Mycobacterium… CONTINUE READING