Synthesis, spectroscopic, and structural characterization of the first aqueous cobalt(II)-citrate complex: toward a potentially bioavailable form of cobalt in biologically relevant fluids

@article{Matzapetakis2000SynthesisSA,
  title={Synthesis, spectroscopic, and structural characterization of the first aqueous cobalt(II)-citrate complex: toward a potentially bioavailable form of cobalt in biologically relevant fluids},
  author={Manolis Matzapetakis and Maria Dakanali and Catherine P. Raptopoulou and Vasilis Tangoulis and Aris Terzis and Namdoo Moon and John Giapintzakis and Athanasios Salifoglou},
  journal={JBIC Journal of Biological Inorganic Chemistry},
  year={2000},
  volume={5},
  pages={469-474}
}
Citric acid represents a class of carboxylic acids present in biological fluids and playing key roles in biochemical processes in bacteria and humans. Its ability to promote diverse coordination chemistries in aqueous media, in the presence of metal ions known to act as trace elements in human metabolism, earmarks its involvement in a number of physiological functions. Cobalt is known to be a central element of metabolically important biomolecules, such as B12, and therefore its biospeciation… CONTINUE READING