Synthesis, lipophilicity study and in vitro evaluation of some rodenticides as acetylcholinesterase reversible inhibitors.

@article{Ghadimi2008SynthesisLS,
  title={Synthesis, lipophilicity study and in vitro evaluation of some rodenticides as acetylcholinesterase reversible inhibitors.},
  author={Saied Ghadimi and Seyed Latif Mousavi and Zahra Javani},
  journal={Journal of enzyme inhibition and medicinal chemistry},
  year={2008},
  volume={23 2},
  pages={213-7}
}
The anti-AChE activity of phosphoramidates has been noticed for many years. Because of the wide application of phosphoramidates in recent years, there has been a continuing research for synthesis, purification and identification of effective and safe derivatives. In this study some rodenticides with the general formula Me(2)NP(O)(p-OC(6)H(4)-X)(2), where X… CONTINUE READING