Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4'-methylmethcathinone (mephedrone): a new "legal high".

@article{Santali2011SynthesisFC,
  title={Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4'-methylmethcathinone (mephedrone): a new "legal high".},
  author={Eman Y Santali and Anna-Karina Cadogan and Niamh Nic Da{\'e}id and Kathleen A Savage and Oliver B Sutcliffe},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2011},
  volume={56 2},
  pages={246-55}
}
The recent global increase in the abuse of 4'-methylmethcathinone and related compounds has developed a requirement for full chemical characterisation of these products. In this work we present full synthetic and chemical characterisation data and supplemental information for mephedrone synthesised as both the hydrobromide and hydrochloride salt. Additionally we report the first fully validated chromatographic methods for the detection and quantitative analysis of the substance both in its pure… CONTINUE READING

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