Synthesis, characterizations of dye-doped silica nanoparticles and their application in labeling cells.

@article{Zhang2012SynthesisCO,
  title={Synthesis, characterizations of dye-doped silica nanoparticles and their application in labeling cells.},
  author={Nianchun Zhang and Enyong Ding and Xue Feng and Yang Xu and Huaihong Cai},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2012},
  volume={89},
  pages={133-8}
}
Spherical silica nanoparticles coated with fluorescein isothiocyanate (FITC) dyes were prepared by using an improved Stöber method. The nanoparticles were ~55 nm in diameter and were essentially mono-dispersed in aqueous solutions. The fluorescence excitation and emission spectra of the nano-composite particles showed no obvious shift compared with that of the free FITC in the aqueous solution. The photostability of FITC doped SiO(2) nanoparticles (FDSN) increased about three-fold, compared to… CONTINUE READING
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