Synthesis, characterization and in vitro anti-invasive activity screening of polyphenolic and heterocyclic compounds.

@article{Parmar2003SynthesisCA,
  title={Synthesis, characterization and in vitro anti-invasive activity screening of polyphenolic and heterocyclic compounds.},
  author={V. S. Parmar and N. Sharma and M. Husain and A. Watterson and J. Kumar and L. Samuelson and A. Cholli and A. Prasad and Ajay Kumar and S. Malhotra and Naresh Kumar and A. Jha and Amarjit Singh and I. Singh and Himanshu and A. Vats and N. Shakil and S. Trikha and S. Mukherjee and Sunil K. Sharma and Sanjay K. Singh and H. N. Jha and C. Olsen and C. Stove and M. Bracke and M. Mareel},
  journal={Bioorganic \& medicinal chemistry},
  year={2003},
  volume={11 6},
  pages={
          913-29
        }
}
Invasion is the hallmark of malignant tumors, and is responsible for the bad prognosis of the untreated cancer patients. The search for anti-invasive treatments led us to screen compounds of different classes for their effect in an assay for invasion. Thirty-nine new compounds synthesized in the present study along with 56 already reported compounds belonging mainly to the classes of lactones, pyrazoles, isoxazoles, coumarins, desoxybenzoins, aromatic ketones, chalcones, chromans, isoflavanones… Expand
DESIGN AND SYNTHESIS OF NEW HETEROCYCLIC COMPOUNDS TO OVERCOME MICROBIAL RESISTANCE
Pyrrolyl Pyrazoline Carbaldehydes as Enoyl-ACP Reductase Inhibitors: Design, Synthesis and Antitubercular Activity
Original article SYNTHESIS AND ANTICANCER ACTIVITY OF SOME BISQUINOXALINE DERIVATIVES
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