Synthesis, characterization and biological evaluation of piperidine-4-carboxamide deriva-tives in mice


Present work comprises of synthesis of sulfonamide and amide derivatives of piperidine-4-carboxamide via amino–dechlorination and amino-de-alkoxylation reaction. Structure of the analogues was confirmed by different techniques i.e. IR and H NMR. Piperidine derivatives had found to be potent dopamine reuptake inhibitor. Synthesized derivatives were also… (More)


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