Synthesis, characterization, and conformational studies of N-t-butyloxycarbonyl-oligo-l-leucine methyl esters

@inproceedings{Bonora1974SynthesisCA,
  title={Synthesis, characterization, and conformational studies of N-t-butyloxycarbonyl-oligo-l-leucine methyl esters},
  author={Gian Maria Bonora and A A Maglione and Claudio Toniolo},
  year={1974}
}
Abstract The conformational properties of N- t-butyloxycarbonyl-oligo- l -leucine methyl esters were examined in anhydrous and aqueous organic solvents. This study demonstrates that these oligomers may exist in predominantly β-associated or unordered conformations depending upon the solvent. The β-structure, which appears at the pentamer in ethylene glycol (EG) and trifluoroethanol (TFE)-water (20:80 v/v), could be disrupted by dilution or by increasing the temperature. The stability of the… CONTINUE READING