Synthesis, characterization, and biodistribution of multiple 89Zr-labeled pore-expanded mesoporous silica nanoparticles for PET.

@article{Miller2014SynthesisCA,
  title={Synthesis, characterization, and biodistribution of multiple 89Zr-labeled pore-expanded mesoporous silica nanoparticles for PET.},
  author={Larissa Miller and Gordon Winter and Benjamin Baur and Barbara Witulla and Christoph Solbach and Sven Norbert Reske and Mika Lind{\'e}n},
  journal={Nanoscale},
  year={2014},
  volume={6 9},
  pages={
          4928-35
        }
}
Functional nanoparticles are highly interesting imaging agents for positron emission tomography (PET) due to the possibility of multiple incorporation of positron emitting radionuclides thus increasing the signal strength. Furthermore, long-term nanoparticle biodistribution tests with increased signal-to-noise ratio can be achieved with nanoparticles carrying long-lived isotopes. Mesoporous silica nanoparticles, MSNs, have recently attracted a lot of interest as both imaging agents and carriers… Expand
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