Synthesis, characterization, DNA-binding and biological activity of Zn(II) complexes of sulfadiazine with different amino acids

@article{ElHenawy2015SynthesisCD,
  title={Synthesis, characterization, DNA-binding and biological activity of Zn(II) complexes of sulfadiazine with different amino acids},
  author={Ahmed A. El-Henawy and Ahmed I. Hanafy},
  journal={European Journal of Chemistry},
  year={2015},
  volume={6},
  pages={117-126}
}
New Zn(II) complexes (Zn II -VS, Zn II -LS, Zn II -SS, Zn II -CS and Zn II -MS) of the sulfonamide antibiotic sulfadiazine with different amino acids were prepared and fully characterized by elemental analyses, thermal analysis and IR, UV/Vis and 1 H NMR spectroscopy. The IR and 1 H NMR spectral data show that the ligands behave in a dibasic bidentate fashion coordinating to zinc ion. Interactions of these complexes with DNA were investigated by spectrophotometric method. Moreover, the… Expand

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