Synthesis, antiproliferative and antifungal activities of some 2-(2,4-dihydroxyphenyl)-4H-3,1-benzothiazines.

Abstract

A new method for the synthesis of 4H-3,1-benzothiazine skeleton is described. The compounds were obtained by the reaction of sulfinylbis(2,4-dihydroxythiobenzoyl) with o-substituted anilines bearing an activated methylene group (-CH2OH, -CH2NR1R2), o-aminobenzanilides or 2-aminobenzophenones. The reaction proceeded through thiobenzanilide intermediates… (More)

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@article{Matysiak2006SynthesisAA, title={Synthesis, antiproliferative and antifungal activities of some 2-(2,4-dihydroxyphenyl)-4H-3,1-benzothiazines.}, author={Joanna Matysiak}, journal={Bioorganic & medicinal chemistry}, year={2006}, volume={14 8}, pages={2613-9} }