Synthesis, SAR and pharmacological characterization of novel anthraquinone cation compounds as potential anticancer agents.

Abstract

Emodin, a natural anthraquinone derivative isolated from Rheum palmatum L., has been demonstrated to exhibit good anti-cancer effect. In this study, a series of novel quaternary ammonium salts of emodin, anthraquinone and anthrone were synthesized and their anticancer activities were tested in vitro. The effects of emodin quaternary ammonium salts on cell… (More)
DOI: 10.1016/j.ejmech.2016.10.012

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